Anti-Phospho-CD22 (Y807) Antibody

Primary Antibodies

95348 MW

WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200

B-cell receptor CD22

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

1 mg/ml

Mediates B-cell B-cell interactions. May be involved in
the localization of B-cells in lymphoid tissues. Binds sialylated
glycoproteins; one of which is CD45. Preferentially binds to
alpha-2, 6-linked sialic acid. The sialic acid recognition site can
be masked by cis interactions with sialic acids on the same cell
surface. Upon ligand induced tyrosine phosphorylation in the
immune response seems to be involved in regulation of B-cell
antigen receptor signaling. Plays a role in positive regulation
through interaction with Src family tyrosine kinases and may also
act as an inhibitory receptor by recruiting cytoplasmic
phosphatases via their SH2 domains that block signal transduction
through dephosphorylation of signaling molecules.

Boster Bio Anti-Phospho-CD22 (Y807) Antibody catalog # A01572Y807. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Boster Bio Anti-Phospho-CD22 (Y807) Antibody catalog # A01572Y807. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.