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Anti-Nucleobindin-2 NUCB2 Antibody

Anti-Nucleobindin-2 NUCB2 Antibody

Item no.	BOS-A02400
Manufacturer	Boster
Amount	0.1 mg
Category	Metabolism Regulation of Appetite Immunohistochemistry Western Blot ELISA Immunofluorescence Immunostaining
Format	Liquid
Applications	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Alias	NEFA,HEL-S-109,NEFA,Nucleobindin-2,DNA-binding protein NEFA
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Nucleobindin-2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Molecular Weight	50223 MW
Clonality	Polyclonal
Application Details	Nucleobindin-2 Antibody can be used for detection of Nucleobindin-2 by Western blot starting at 0.5 μg/mL. Antibody validated: Western Blot in rat samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Gene Name	NUCB2
Gene Full Name	Nucleobindin 2
Manufacturer - Specificity	Nucleobindin-2 antibody is predicted to not cross-react with NUCB1.
Background	NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.
Immunogen	Nucleobindin-2 antibody was raised against a 16 amino acid peptide near the center of human Nucleobindin-2. The immunogen is located within amino acids 260 - 310 of Nucleobindin-2.
Contents	Nucleobindin-2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification	Nucleobindin-2 Antibody is affinity chromatography purified via peptide column.
Concentration	1 mg/mL
Manufacturer - Research Category	Obesity
Protein Name	Nucleobindin 2
Protein Function	Calcium-binding protein. May have a role in calcium homeostasis.
Subcellular Localization	Golgi apparatus
Description	Boster Bio Anti-Nucleobindin-2 NUCB2 Antibody (Catalog # A02400). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Predominantly expressed in spleen, testis and normal stomach.
Predicted Reactivity	Bovine
Manufacturer - Cross Reactivity	Nucleobindin-2 antibody is predicted to not cross-react with NUCB1.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A02400-datasheet.pdf

BOS-A02400-safety-datasheet.pdf