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Anti-Renin receptor/ATP6AP2 Antibody Picoband®

Anti-Renin receptor/ATP6AP2 Antibody Picoband®

Item no.	BOS-A02665-3-APC
Manufacturer	Boster
Amount	100 ug
Applications	WB, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	1. Cruciat, C.-M., Ohkawara, B., Acebron, S. P., Karaulanov, E., Reinhard, C., Ingelfinger, D., Boutros, M., Niehrs, C. Requirement of prorenin receptor and vacuolar H(+)-ATPase-mediated acidification for Wnt signaling. Science 327: 459-463, 2010. 2. Demirci, F. Y. K., White, N. J., Rigatti, B. W., Lewis, K. F., Gorin, M. B. Identification, genomic structure, and screening of the vacuolar proton-ATPase membrane sector-associated protein M8-9 gene within the COD1 critical region (Xp11.4). Molec. Vis. 7: 234-239, 2001. Note: Electronic Article. 3. Dubos, A., Castells-Nobau, A., Meziane, H., Oortveld, M. A. W., Houbaert, X., Iacono, G., Martin, C., Mittelhaeuser, C., Lalanne, V., Kramer, J. M., Bhukel, A., Quentin, C., and 10 others. Conditional deletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration. Hum. Molec. Genet. 24: 6736-6755, 2015.
Alias	ATP6AP2; ATP6IP2; CAPER; ELDF10; HT028; MSTP009; PSEC0072; Renin receptor; ATPase H(+-transporting lysosomal accessory protein 2; ATPase H(+-transporting lysosomal-interacting protein 2; ER-localized type I transmembrane adaptor; Embryonic liver differentiation factor 10; N14F; Renin/prorenin receptor; Vacuolar ATP synthase membrane sector-associated protein M8-9; ATP6M8-9; V-ATPase M8.9 subunit [Cleaved into: Renin receptor N-terminal fragment; Renin receptor C-terminal fragment]
Available
Manufacturer - Isotype	Rabbit IgG
Observed Molecular Weight	49 kDa
Calculated Molecular weight	39 kDa
Application Details	Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
Manufacturer - Gene Name	ATP6AP2
Gene Full Name	ATPase H+ transporting accessory protein 2
Background	The renin receptor also known as ATPase H(+)-transporting lysosomal accessory protein 2, or the prorenin receptor, is a protein that in humans is encoded by the ATP6AP2 gene. This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human Renin receptor/ATP6AP2, which shares 100% and 95.8% amino acid (aa) sequence identity with mouse and rat Renin receptor/ATP6AP2, respectively.
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Protein Name	Renin receptor

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 7/31/2025

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