Anti-Transcription factor E2F6 E2F6 Antibody

Primary Antibodies

31844 MW

WB: 1:500-1:2000
IHC/IF: 1:50-1:200
IP/CHIP: 1:50-1:200

Transcription factor E2F6

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

Inhibitor of E2F-dependent transcription. Binds DNA
cooperatively with DP proteins through the E2 recognition site,
5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F
recognition site. E2F6 lacks the transcriptional activation and
pocket protein binding domains. Appears to regulate a subset of
E2F-dependent genes whose products are required for entry into the
cell cycle but not for normal cell cycle progression. May silence
expression via the recruitment of a chromatin remodeling complex
containing histone H3-K9 methyltransferase activity.
Overexpression delays the exit of cells from the S-phase.

Boster Bio Anti-Transcription factor E2F6 E2F6 Antibody catalog # A05062. Tested in WB, IHC, IF, IP, CHIP applications. This antibody reacts with Human, Mouse.