Item no. |
BOS-A05393 |
Manufacturer |
Boster
|
Amount |
100 ul |
Format |
Liquid |
Applications |
WB |
Specific against |
Human (Homo sapiens) |
Host |
Rabbit |
Isotype |
IgG |
Alias |
Cysteinyl leukotriene receptor 1;CysLTR1;Cysteinyl leukotriene D4 receptor;LTD4 receptor;G-protein coupled receptor HG55;HMTMF81;CYSLTR1;CYSLT1; |
Available |
|
Manufacturer - Category |
Primary Antibodies |
Storage Conditions |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Observed Molecular Weight |
38541 MW |
Application Details |
WB, 1:500-1:2000 |
Manufacturer - Gene Name |
CYSLTR1 |
Gene Full Name |
Cysteinyl leukotriene receptor 1 |
Immunogen |
The antiserum was produced against synthesized peptide derived from human CYSLTR1. AA range:131-180 |
Contents |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification |
Immunogen affinity purified |
Protein Function |
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4. |
Subcellular Localization |
Cell membrane; Multi-pass membrane protein. |
Short Description |
Boster Bio Anti-CysLTR1/Cyslt1 Antibody catalog # A05393. Tested in WB applications. This antibody reacts with Human. |
Description |
Boster Bio Anti-CysLTR1/Cyslt1 Antibody catalog # A05393. Tested in WB applications. This antibody reacts with Human. |
Tissue Specificity |
Widely expressed, with highest levels in spleen and peripheral blood leukocytes. Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
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