Anti-IL-22 Receptor IL22RA1 Antibody

IL-22 Receptor antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Polyclonal

IL22RA1

A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family. IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.

IL-22 Receptor Antibody is supplied in PBS containing 0.02% sodium azide.

1 mg/ml

Interleukin 22 receptor, alpha 1

Membrane; Single-pass type I membrane protein.

Boster Bio Anti-IL-22 Receptor IL22RA1 Antibody (Catalog # A05705). Tested in ELISA, WB applications. This antibody reacts with Human, Rat.

Bovine, Mouse