Item no. |
BOS-A06260-APC |
Manufacturer |
Boster
|
Amount |
100 ug |
Applications |
WB, IHC, ELISA |
Specific against |
Human (Homo sapiens), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
Citations |
1. Bao, Y.-C., Tsuruga, H., Hirai, M., Yasuda, K., Yokoi, N., Kitamura, T., Kumagai, H. Identification of a human cDNA sequence which encodes a novel membrane-associated protein containing a zinc metalloprotease motif. DNA Res. 10: 123-128, 2003. 2. Fessler, E., Eckl, E.-M., Schmitt, S., Mancilla, I. A., Meyer-Bender, M. F., Hanf, M., Philippou-Massier, J., Krebs, S., Zischka, H., Jae, L. T. A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol. Nature 579: 433-437, 2020. 3. Guo, X., Aviles, G., Liu, Y., Tian, R., Unger, B. A., Lin, Y.-H. T., Wiita, A. P., Xu, K., Correia, M. A., Kampmann, M. Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway. Nature 579: 427-432, 2020. |
Alias |
OMA1, MPRP1, Metalloendopeptidase OMA1, mitochondrial, EC 3.4.24.-, Metalloprotease-related protein 1, MPRP-1, Overlapping with the m-AAA protease 1 homolog |
Available |
|
Manufacturer - Category |
Primary Antibodies |
Manufacturer - Isotype |
Rabbit IgG |
Storage Conditions |
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing. |
Molecular Weight |
60 kDa |
Manufacturer - Format |
Lyophilized |
Calculated Molecular weight |
60 kDa |
Clonality |
Polyclonal |
Application Details |
Western blot, 0.25-0.5 μg/ml, Human, Rat Immunohistochemistry, 2-5 μg/ml, Human ELISA, 0.1-0.5 μg/ml |
Gene Name |
OMA1 |
Gene Full Name |
OMA1 zinc metallopeptidase |
Background |
Enables metalloendopeptidase activity. Involved in several processes, including HRI-mediated signaling; proteolysis; and regulation of mitochondrion organization. Located in mitochondrial inner membrane. Is active in mitochondrial intermembrane space. |
Immunogen |
E.coli-derived human OMA1 recombinant protein (Position: K256-H483). Human OMA1 shares 83.3% amino acid (aa) sequence identity with both mouse and rat OMA1. |
Contents |
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4. |
Purification |
Immunogen affinity purified. |
Reconstitution |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Protein Name |
Metalloendopeptidase OMA1, mitochondrial |
Description |
Boster Bio Anti-OMA1 Antibody Picoband® catalog # A06260. Tested in WB, IHC, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.