Comparison

Anti-VAMP8/Endobrevin Rabbit Monoclonal Antibody European Partner

Item no. BOS-M02338-30ul
Manufacturer Boster
Amount 30 ul
Format Liquid
Applications WB, FC, IF, IP, IHC, ICC
Clone AOBO-22
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
Alias Vesicle-associated membrane protein 8 ;VAMP-8 ;Endobrevin ;EDB ;VAMP8 ;
Available
Manufacturer - Category
Rabbit Monoclonal Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
11 kDa
Calculated Molecular weight
11438 MW
Clonality
Monoclonal
Application Details
WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50
FC 1:50
Manufacturer - Gene Name
VAMP8
Gene Full Name
Vesicle-associated membrane protein 8
Immunogen
A synthesized peptide derived from human VAMP8
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Cell Type Marker, Immunology, Innate Immunity, Macrophage/Inflammation, Neuron Marker, Neuroscience, Neurotransmission, Secretory Vesicles, Synapse Marker
Protein Name
Lysosome-associated membrane glycoprotein 2 (Lamp2)
Protein Function
SNAREs, soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex (PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets (PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells (By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells (By similarity). Involved in the homotypic fusion of early and late endosomes (By similarity).
Subcellular Localization
Lysosome membrane; Single-pass type IV membrane protein. Early endosome membrane; Single-pass type IV membrane protein. Late endosome membrane; Single-pass type IV membrane protein. Cell membrane; Single-pass type IV membrane protein. Perinuclear vesicular structures of the early and late endosomes, coated pits, and trans-Golgi (By similarity). Sub-tight junctional domain in retinal pigment epithelium cells. Midbody region during cytokinesis. Lumenal oriented, apical membranes of nephric tubular cell (By similarity). Cycles through the apical but not through the basolateral plasma membrane (By similarity). Apical region of acinar cells; in zymogen granule membranes (By similarity).
Description
Boster Bio Anti-VAMP8/Endobrevin Rabbit Monoclonal Antibody catalog # M02338. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Platelets.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 30 ul
Available: In stock
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