Comparison

Anti-Interleukin-10 IL10 Antibody Picoband® European Partner

Item no. BOS-PA1354
Manufacturer Boster
Amount 100 ug/vial
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
Citations 1. Eskdale J, Kube D, Tesch H, Gallagher G (1997). "Mapping of the human IL10 gene and further characterization of the 5' flanking sequence".
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Interleukin-10;IL-10;Cytokine synthesis inhibitory factor;CSIF;IL10;
Similar products CSIF antibody, Cytokine Synthesis Inhibitory Factor antibody, GVHDS antibody, IL 10 antibody, IL-10 antibody, IL10 antibody, IL10A antibody, Interleukin 10 antibody, Interleukin-10 antibody, Interleukin10 antibody, MGC126450 antibody, MGC126451 antibody, T-cell growth inhibitory factor antibody, TGIF antibody
Available
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
60 kDa
Calculated Molecular weight
20517 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml, Human
Manufacturer - Gene Name
IL10
Gene Full Name
Interleukin-10
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al. (1992) showed that the mouse Il 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al. (1997) mapped the IL10 gene to the junction between 1q31 and 1q32.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human IL10.
Contents
Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Adaptive Immunity, Cancer, Cytokines, Immunology, Innate Immunity, Interleukins, Tumor Immunology
Protein Name
Interleukin-10(IL-10)
Protein Function
Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
Subcellular Localization
Secreted.
Description
Boster Bio Anti-Interleukin-10 IL10 Antibody catalog # PA1354. Tested in WB applications. This antibody reacts with Human.
Tissue Specificity
Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.
Sequence Similarities
Belongs to the IL-10 family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?