Comparison

Anti-Heme oxygenase 2/HMOX2 Antibody Picoband® European Partner

Item no. BOS-PB9213
Manufacturer Boster
Amount 100 ug/vial
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB, IHC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Sensitivity <5pg/ml
Citations 1. McCoubrey WK Jr, Ewing JF, Maines MD (Jun 1992). "Human heme oxygenase-2: characterization and expression of a full-length cDNA and evidence suggesting that the two HO-2 transcripts may differ by choice of polyadenylation signal". Arch Biochem Biophys 295 (1): 13–20.
2. "Entrez Gene: HMOX2 heme oxygenase (decycling) 2"
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Heme oxygenase 2;HO-2;1.14.99.3;HMOX2;HO2;
Similar products Heme oxygenase (decycling) 2 antibody, Heme oxygenase (decyclizing) 2 antibody, Heme oxygenase 2 antibody, HMOX 2 antibody, HMOX2 antibody, HMOX2 protein antibody, HMOX2_HUMAN antibody, HO 2 antibody, HO-2 antibody, HO2 antibody, OTTHUMP00000159847 antibody
Available
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
38 kDa
Calculated Molecular weight
36033 MW
Clonality
Polyclonal
Application Details
Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Human, By Heat
Western blot, 0.1-0.5?g/ml, Human
Manufacturer - Gene Name
HMOX2
Gene Full Name
Heme oxygenase 2
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Heme oxygenase 2 (HMOX2), also known as HO-2, is an enzyme that in humans is encoded by the HMOX2 gene. It is mapped to 16p13.3. HMOX2 belongs to the heme oxygenase family. Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
Immunogen
E.coli-derived human HMOX2 recombinant protein (Position: S2-M316). Human HMOX2 shares 89% and 90% amino acid (aa) sequences identity with mouse and rat HMOX2, respectively.
Contents
Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Cancer, Cancer Metabolism, Cell Biology, Metabolism, Metabolism Processes, Oxidative Stress, Pathways and Processes, Redox Metabolism, Response To Hypoxia
Protein Name
Heme oxygenase 2
Protein Function
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
Subcellular Localization
Microsome. Endoplasmic reticulum.
Description
Boster Bio Anti-Heme oxygenase 2/HMOX2 Antibody Picoband® catalog # PB9213. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Sequence Similarities
Belongs to the heme oxygenase family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
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