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Anti-VIP Receptor 1/VIPR1 Antibody Picoband® European Partner

Item no. BOS-PA1756
Manufacturer Boster
Amount 100 ug/vial
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
Citations 1. Couvineau, A., Rouyer-Fessard, C., Darmoul, D., Maoret, J.-J., Carrero, I., Ogier-Denis, E., Laburthe, M. Human intestinal VIP receptor: cloning and functional expression of two cDNA encoding proteins with different N-terminal domains. Biochem. Biophys. Res. Commun. 200: 769-776, 1994.
2. Sreedharan, S. P., Huang, J.-X., Cheung, M.-C., Goetzl, E. J. Structure, expression, and chromosomal localization of the type I human vasoactive intestinal peptide receptor gene. Proc. Nat. Acad. Sci. 92: 2939-2943, 1995.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Vasoactive intestinal polypeptide receptor 1;VIP-R-1;Pituitary adenylate cyclase-activating polypeptide type II receptor;PACAP type II receptor;PACAP-R-2;PACAP-R2;VPAC1;VIPR1;
Similar products FLJ41949 antibody, HVR 1 antibody, HVR1 antibody, PACAP R 2 antibody, PACAP type II receptor antibody, PACAP-R-2 antibody, PACAP-R2 antibody, Pituitary adenylate cyclase activating polypeptide receptor type II antibody, Pituitary adenylate cyclase activating polypeptide type II receptor antibody, Pituitary adenylate cyclase-activating polypeptide type II receptor antibody, RCD1 antibody, RDC 1 antibody, RDC1 antibody, V1RG antibody, VAPC 1 antibody, VAPC1 antibody, Vasoactive intestinal peptide receptor 1 antibody, Vasoactive intestinal polypeptide receptor 1 antibody, Vasoactive intestinal polypeptide receptor 1 precursor antibody, VIP R 1 antibody, VIP receptor type I antibody, VIP-R-1 antibody, VIPR 1 antibody, VIPR antibody, VIPR1 antibody, VIPR1_HUMAN antibody, VIRG antibody, VPAC 1 antibody, VPAC1 antibody, VPCAP1R antibody
Available
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
52 kDa
Calculated Molecular weight
51547 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml, Human, Mouse, Rat
Manufacturer - Gene Name
VIPR1
Gene Full Name
Vasoactive intestinal polypeptide receptor 1
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
VIPR1 (Vasoactive intestinal polypeptide receptor 1), also known as VIPR, HVR1, is a protein that in humans is encoded by the VIPR1 gene. Distinct subsets of neural, respiratory, gastrointestinal, and immune cells bear specific high-affinity G protein-coupled receptors for VIP, such as VIPR1. The VIPR1 gene is mapped on 3p22.1. The VIPR1 gene was found to span approximately 22 kb and to be comprised of 13 exons (ranging from 42 to 1, 400 bp) and 12 introns (ranging from 0.3 to 6.1 kb). One encodes a VIP receptor consisting of 460 amino acids and having 7 putative transmembrane domains, as do other G protein-coupled receptors. Patients with idiopathic achalasia show a significant difference in the distribution of SNPs affecting VIPR1.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human VIP Receptor 1, identical to the related rat and mouse sequences.
Contents
Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Calcium Channels, Calcium Signaling, Signal Transduction, Signaling Pathway
Protein Name
Vasoactive intestinal polypeptide receptor 1(VIP-R-1)
Protein Function
This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38.
Subcellular Localization
Cell membrane; Multi-pass membrane protein.
Description
Boster Bio Anti-VIP Receptor 1/VIPR1 Antibody catalog # PA1756. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T- cell lines Peer, MOLT-4, HSB and YT.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
available

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