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Anti-Pro-epidermal growth factor EGF Antibody Picoband®

Anti-Pro-epidermal growth factor EGF Antibody Picoband®

Item no.	BOS-PA1398
Manufacturer	Boster
Amount	100 ug/vial
Category	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Cell Biology Cell Culture Cytokines Immunohistochemistry Western Blot Primary Antibodies By Organ Bladder Cancer
Type	Antibody Polyclonal
Format	Lyophilized
Applications	WB, IHC
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
Citations	1. Brissenden, J. E., Ullrich, A., Francke, U.Chromosomal mapping of loci for insulin-like growth factors I and II and for epidermal growth factor in man.Am. J. Hum. Genet.36: 133S-only, 1984. 2. Carpenter G, Cohen S (May 1990). "Epidermal growth factor". The Journal of Biological Chemistry 265 (14): 7709–12. 3. Herbst RS (2004). "Review of epidermal growth factor receptor biology". International Journal of Radiation Oncology, Biology, Physics 59 (2 Suppl): 21–6.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Pro-epidermal growth factor;EGF;Epidermal growth factor;Egf;
Similar products	Beta urogastrone antibody, EGF antibody, Egf antibody, EGF_HUMAN antibody, Epidermal Growth Factor antibody, HOMG4 antibody, OTTHUMP00000219721 antibody, OTTHUMP00000219722 antibody, Pro epidermal growth factor antibody, URG antibody, Urogastrone antibody
Available
Specificity	No cross reactivity with other proteins.
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	40 kDa
Calculated Molecular weight	133072 MW
Clonality	Polyclonal
Application Details	Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Mouse, By Heat Western blot, 0.1-0.5?g/ml, Mouse
Manufacturer - Gene Name	EGF
Gene Full Name	Pro-epidermal growth factor
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Epidermal growth factor (EGF) is a growth factor that plays an important role in the regulation of cell growth, proliferation and differentiation by binding to its receptor EGFR. EGF locus is mapped to 4q21-4qter. Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bones. EGF results in cellular proliferation, differentiation, and survival while plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of mouse EGF.
Contents	Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Growth Factors, Growth Factors/Hormones, Signal Transduction
Protein Name	Pro-epidermal growth factor(EGF)
Protein Function	EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
Subcellular Localization	Membrane; Single-pass type I membrane protein.
Description	Boster Bio Anti-Pro-epidermal growth factor EGF Antibody catalog # PA1398. Tested in IHC, WB applications. This antibody reacts with Mouse.
Tissue Specificity	Expressed on activated B-cells.
Sequence Similarities	Contains 9 EGF-like domains.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-PA1398-datasheet.pdf

BOS-PA1398-safety-datasheet.pdf