Comparison

Anti-VEGFB Antibody Picoband® European Partner

Item no. BOS-A04494-2
Manufacturer Boster
Amount 100 ug/vial
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB, IHC, ELISA
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
Citations 1. Gerace, L, Cirenei, N., Cappelletti, M., Petraroli, R., Sebastiani, F., Marziliano, N. Assignment of the mouse Vegfb gene to mouse chromosome 19B by in situ hybridization. Cytogenet. Cell Genet. 95: 242-243, 2001.
2. Silvestre, J.-S., Tamarat, R., Ebrahimian, T. G., Le-Roux, A., Clergue, M., Emmanuel, F., Duriez, M., Schwartz, B., Branellec, D., Levy, B. I. Vascular endothelial growth factor-B promotes in vivo angiogenesis. Circ. Res. 93: 114-123, 2003.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF; Vegfb; Vrf
Available
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
29 kDa
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml

Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml

ELISA, 0.1-0.5?g/ml
Manufacturer - Gene Name
Vegfb
Gene Full Name
vascular endothelial growth factor B
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Vascular endothelial growth factor B also known as VEGF-B is a protein that, in humans, is encoded by the VEGF-B gene. VEGF-B is a growth factor that belongs to the vascular endothelial growth factor family, of which VEGF-A is the best-known member. In contrast to VEGF-A, VEGF-B plays a less pronounced role in the vascular system: Whereas VEGF-A is important for the formation of blood vessels, such as during development or in pathological conditions, VEGF-B seems to play a role only in the maintenance of newly formed blood vessels during pathological conditions. It also plays an important role on several types of neurons. And it is important for the protection of neurons in the retina and thecerebral cortex during stroke and of motoneurons during motor neuron diseases such as amyotrophic lateral sclerosis.
Immunogen
E. coli-derived rat VEGFB recombinant protein (Position: P22-A207).
Contents
Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Angiogenesis, Cancer, Cardiovascular, Growth Factors, Growth Factors/Hormones, Invasion/Microenvironment, Neurogenesis, Neurology Process, Neuroscience, Signal Transduction
Protein Function
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis (By similarity).
Subcellular Localization
Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
Description
Boster Bio Anti-VEGFB Antibody Picoband® catalog # A04494-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
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