Anti-Bid Antibody Picoband®

Primary Antibodies

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

21952 MW

Western blot, 0.1-0.5?g/ml, Mouse

Immunohistochemistry (Paraffin-embedded Section), 2-5?g/ml, Mouse, Rat By Heat

Flow Cytometry (Fixed), 1-3 ?g/1x10⁶ cells, Human

BH3-interacting domain death agonist

BID (BH3-Interacting Domain Death Agonist), is a pro-apoptotic member of the Bcl-2 protein family. The BCL2 family of proteins consists of both antagonists and agonists that regulate apoptosis and compete through dimerization. By fluorescence in situ hybridization, Wang et al. (1998) mapped the human BID gene to 22q11. Luo et al. (1998) reported the purification of a cytosolic protein that induces cytochrome c release from mitochondria in response to caspase-8, the apical caspase activated by cell surface death receptors such as FAS and TNF.

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.

Apoptosis, Apoptotic Markers, Cancer, Cell Biology, Cell Death, Intracellular, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways and Processes

Induces caspases and apoptosis. Counters the protective effect of Bcl-2. The major proteolytic product p15 BID allows the release of cytochrome c.

Boster Bio Anti-Bid Antibody catalog # PA2015. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat.

Contains 1 C1q domain.