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Anti-Human CD5 DyLight® 488 conjugated Antibody

Anti-Human CD5 DyLight® 488 conjugated Antibody

Item no.	BOS-A00480-Dyl488
Manufacturer	Boster
Amount	100 ug/vial
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	FC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	DyLight 488
Citations	1. Lundell, A.-C., Johansen, S., Adlerberth, I., Wold, A. E., Hesselmar, B., Rudin, A. High proportion of CD5+ B cells in infants predicts development of allergic disease. J. Immun. 193: 510-518, 2014. 2. Zhang, C., Xin, H., Zhang, W., Yazaki, P. J., Zhang, Z., Le, K., Li, W., Lee, H., Kwak, L., Forman, S., Jove, R., Yu, H. CD5 binds to interleukin-6 and induces a feed-forward loop with the transcription factor STAT3 in B cells to promote cancer. Immunity 44: 913-923, 2016.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	T-cell surface glycoprotein CD5,Lymphocyte antigen T1/Leu-1,CD5,CD5,LEU1
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Observed Molecular weight	39 kDa
Clonality	Polyclonal
Application Details	Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells
Gene Name	CD5
Gene Full Name	CD5 molecule
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	CD5 is a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. In humans, the gene is located on the long arm of chromosome 11. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human CD5, which shares 92.1% and 89.5% amino acid (aa) sequence identity with mouse and rat CD5, respectively.
Contents	Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Concentration	0.5mg/ml
Manufacturer - Research Category	Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells, T Cells, T Lymphocytic Lineage
Protein Function	May act as a receptor in regulating T-cell proliferation.
Subcellular Localization	Cell membrane; Single-pass type I membrane protein.
Description	Boster Bio Anti-Human CD5 DyLight® 488 conjugated Antibody catalog # A00480-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-A00480-Dyl488-datasheet.pdf

BOS-A00480-Dyl488-safety-datasheet.pdf