Anti-TrkB (Ab-705) NTRK2 Antibody

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Predicted MW: 145kd

Western blotting: 1:500~1:1000

Immunofluorescence: 1:100~1:200

Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
Woronowicz A, et al. Glycobiology. 2007 Jan; 17(1):10-24. Mojsilovic-Petrovic J, et al. J Neurosci. 2006 Sep 6; 26(36):9250-63. Lewis MA, et al. Mol Pharmacol. 2006 Apr; 69(4):1396-404. Cai D, et al. Physiol Genomics. 2006 Feb 14; 24(3):191-7.

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

1 mg/ml

Boster Bio Anti-TrkB (Ab-705) NTRK2 Antibody (Catalog # A01388-1). Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.