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Anti-Cyclin-G-associated kinase GAK Antibody

Anti-Cyclin-G-associated kinase GAK Antibody

Item no.	BOS-A04246
Manufacturer	Boster
Amount	100 ul
Category	Neuroscience Neural Signaling Antibodies Western Blot Primary Antibodies
Type	Antibody
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cyclin-G-associated kinase;2.7.11.1;GAK;
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	143191 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000
Manufacturer - Gene Name	GAK
Gene Full Name	Cyclin-G-associated kinase
Background	Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. Kimura S.H., Genomics 44:179-187(1997). The MGC Project Team; Genome Res. 14:2121-2127(2004). Greener T., J. Biol. Chem. 275:1365-1370(2000).
Immunogen	Synthesized peptide derived from Internal of human GAK.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	Cell Biology, Cell Cycle, Kinases/Phosphatases, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction
Protein Function	Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
Subcellular Localization	Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network. Cell junction, focal adhesion. Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focal adhesions.
Short Description	Boster Bio Anti-Cyclin-G-associated kinase GAK Antibody (Catalog # A04246). Tested in WB, IHC applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-Cyclin-G-associated kinase GAK Antibody (Catalog # A04246). Tested in WB, IHC applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Ubiquitous. Highest in testis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A04246-datasheet.pdf

BOS-A04246-safety-datasheet.pdf