« Back
Home /
Anti-ARHGEF12/Larg Antibody

Anti-ARHGEF12/Larg Antibody

Item no.	BOS-A06802
Manufacturer	Boster
Amount	100 ul
Category	Neuroscience Neural Signaling Antibodies Cell Biology Cytoskeleton Western Blot Primary Antibodies small GTPases Rho Subfamily
Type	Antibody
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Rho guanine nucleotide exchange factor 12;Leukemia-associated RhoGEF;ARHGEF12;KIAA0382, LARG;
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	173232 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000
Manufacturer - Gene Name	ARHGEF12
Gene Full Name	Rho guanine nucleotide exchange factor 12
Background	May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Kourlas P.J., Proc. Natl. Acad. Sci. U.S.A. 97:2145-2150(2000). The MGC Project Team, Genome Res. 14:2121-2127(2004). Nagase T., DNA Res. 4:141-150(1997).
Immunogen	Synthesized peptide derived from internal of human ARHGEF12.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Protein Function	May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
Subcellular Localization	Cytoplasm. Membrane. Translocated to the membrane upon stimulation.
Short Description	Boster Bio Anti-ARHGEF12/Larg Antibody (Catalog # A06802). Tested in WB applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-ARHGEF12/Larg Antibody (Catalog # A06802). Tested in WB applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Ubiquitously expressed. Isoform 2 is found in jejunum and testis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A06802-datasheet.pdf

BOS-A06802-safety-datasheet.pdf