Comparison

Anti-ILKAP/Pp2C Delta Antibody European Partner

Item no. BOS-A08074
Manufacturer Boster
Amount 100 ul
Category
Type Antibody
Format Liquid
Applications WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Integrin-linked kinase-associated serine/threonine phosphatase 2C;ILKAP;3.1.3.16;ILKAP;
Available
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
42907 MW
Clonality
Polyclonal
Application Details
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Manufacturer - Gene Name
ILKAP
Gene Full Name
Integrin-linked kinase-associated serine/threonine phosphatase 2C
Background
Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.
Leung-Hagesteijn C., EMBO J. 20:2160-2170(2001).
Wiemann S., Genome Res. 11:422-435(2001).
Hillier L.W., Nature 434:724-731(2005).
Immunogen
Synthesized peptide derived from internal of human ILKAP.
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Manufacturer - Research Category
Protein Phosphorylation, Ser/Thr Phosphatases, Signal Transduction
Protein Function
Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.
Subcellular Localization
Cytoplasm.
Short Description
Boster Bio Anti-ILKAP/Pp2C Delta Antibody (Catalog # A08074). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Description
Boster Bio Anti-ILKAP/Pp2C Delta Antibody (Catalog # A08074). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various smooth muscle tissues.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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