Anti-human CD11b Itgam Monoclonal Antibody PE Conjugated, Flow Validated

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Monoclonal

Itgam

ITGAM (Integrin Alpha-M), also called CD11B or Mo1 ALPHA SUBUNIT (MO1A), is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (alphaMbeta2) molecule. A major surface antigen family on human leukocytes includes complement receptor type 3 (CR3A; also called ITGAM, Mac1, or Mo1), lymphocyte function-associated (LFA) antigen type 1 (ITGAL), and p150, 95 (ITGAX). By in situ hybridization, Corbi et al. (1988) demonstrated that the genes encoding the alpha subunits of LFA1 (ITGAL), Mac1, and p150, 95 (ITGAX), all of which are involved in leukocyte adhesion, constitute a cluster on 16p13.1-p11. Callen et al. (1991) narrowed the assignment to 16p11.2. Inflammation plays an essential role in the initiation and progression of atherosclerosis. Simon et al. (2000) presented evidence that it also has a role in vascular repair after mechanical arterial injury (i.e., percutaneous transluminal coronary angioplasty, or PTCA).

PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Integrin alpha-M

Membrane; Single-pass type I membrane protein.

Boster Bio Anti-human CD11b Itgam Monoclonal Antibody PE Conjugated, Flow Validated (Catalog# FC00144-PE). Tested in Flow Cytometry application(s). This antibody reacts with Human.

Belongs to the integrin alpha chain family.