Anti-Alpha-1-Trypsin SERPINA1 Antibody Peroxidase Conjugated

Primary Antibodies

46737 MW

Anti-Alpha 1 anti-Trypsin Antibody is tested by ELISA and western blot. This product detects a single band of the expected apparent molecular weight (~47 kDa) and for ELISA. Researchers should determine optimal titers for applications that are not stated below.

SERPINA1

Anti-Alpha 1-Anti-Trypsin Antibody detects a1-Anti-Trypsin protein. a1-Anti-Trypsin is an inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Anti-Trypsin irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form of Antitrypsin inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Defects in SERPINA1 are the cause emphysema, liver cirrhosis and liver failure. Environmental factors, particularly cigarette smoking, greatly increase the risk of emphysema at an earlier age. Anti-Alpha-1-Anti-Trypsin Antibody is ideal for investigators involved in Cell Signaling, Signal Transduction and Cancer research.

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free, 0.01% (w/v) Gentamicin Sulfate. Do NOT add Sodium Azide!

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Apoptosis, Cancer, Cancer Metabolism, Cardiovascular, Cell Biology, Intracellular, Kinases, Metabolism, Metabolism Processes, Pathways and Processes, Protease Inhibitors, Proteolysis/Ubiquitin, Response To Hypoxia, Serum Proteins

Secreted. Endoplasmic reticulum. The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum.

Boster Bio Anti-Alpha-1-Trypsin SERPINA1 Antibody Peroxidase Conjugated (Catalog # H00720). Tested in ELISA, WB applications. This antibody reacts with Human.