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Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody

Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody

Item no.	BOS-M00048
Manufacturer	Boster
Amount	100 ul
Category	Neuroscience Neural Signaling Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC
Clone	DCB-3
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Caspase-1;CASP-1;3.4.22.36;Interleukin-1 beta convertase;IL-1BC;Interleukin-1 beta-converting enzyme;ICE;IL-1 beta-converting enzyme;p45;Caspase-1 subunit p20;Caspase-1 subunit p10;CASP1;IL1BC, IL1BCE;
Available
Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	83, 88 kDa
Calculated Molecular weight	45159 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:50-1:200
Manufacturer - Gene Name	CASP1
Gene Full Name	Caspase-1
Immunogen	A synthesized peptide derived from human Caspase-1
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Apoptosis, Caspases, Cell Biology, Intracellular
Protein Name	P2X purinoceptor 1
Protein Function	Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Subcellular Localization	Cytoplasm.
Description	Boster Bio Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody catalog # M00048. Tested in WB, IHC applications. This antibody reacts with Human, Rat.
Tissue Specificity	Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M00048-datasheet.pdf

BOS-M00048-safety-datasheet.pdf