Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348

Rabbit IgG

68996 MW

Immunohistochemistry (IHC): 1:500-1:1000 dilution

WB: 1:1000-1:20000 dilution.

Prostaglandin G/H synthase 2

50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.

Boster Bio Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348 (Catalog # M00084-2). Tested in IHC, WB applications. This antibody reacts with Human.