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Anti-AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Monoclonal Antibody European Partner

Item no. BOS-M00522
Manufacturer Boster
Amount 100 ug
Category
Type Antibody Monoclonal
Format Liquid
Applications FC, IF, IHC
Clone SPM334
Specific against Human (Homo sapiens), Monkey (Cynomolgus, Simian), Dog (Canine, Canis lupus familiaris), Pig (Porcine, Sus scrofa domesticus)
Host Mouse
Isotype IgG2a Kappa
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Alpha-fetoprotein;Alpha-1-fetoprotein;Alpha-fetoglobulin;AFP;HPAFP;
Available
Manufacturer - Category
Primary Antibodies, Monoclonal Antibodies
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Observed Molecular Weight
68678 MW
Clonality
Monoclonal
Application Details
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.
Manufacturer - Gene Name
AFP
Gene Full Name
Alpha-fetoprotein
Background
This monoclonal antibody recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP). This monoclonal antibody is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.
Immunogen
Alpha feto protein (AFP) Purified from serum of a hepatoma patient
Contents
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Purification
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.
Concentration
Purified antibody with BSA and azide at 200ug/ml
Protein Function
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
Subcellular Localization
Cytoplasmic
Short Description
Boster Bio Anti-AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Monoclonal Antibody (Catalog # M00522). Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human, Monkey, Dog, Pig.
Description
Boster Bio Anti-AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Monoclonal Antibody (Catalog # M00522). Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human, Monkey, Dog, Pig.
Tissue Specificity
Plasma. Synthesized by the fetal liver and yolk sac.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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