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Anti-MRP1 / ABCC1 (Multidrug Resistance Related Protein 1) Monoclonal Antibody

Anti-MRP1 / ABCC1 (Multidrug Resistance Related Protein 1) Monoclonal Antibody

Item no.	BOS-M00872
Manufacturer	Boster
Amount	100 ug
Category	Food Safety Hormones Antibodies Immunohistochemistry Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, FC, ELISA
Clone	MRP1/1343
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Multidrug resistance-associated protein 1;ATP-binding cassette sub-family C member 1;Leukotriene C (4) transporter;LTC4 transporter;ABCC1;MRP, MRP1;
Available
Manufacturer - Category	Primary Antibodies, Monoclonal Antibodies, 2279
Storage Conditions	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Observed Molecular Weight	171591 MW
Clonality	Monoclonal
Application Details	ELISA (For coating, order antibody without BSA) Flow Cytometry (1-2ug/million cells) Western Blot (1-2ug/ml) Optimal dilution for a specific application should be determined.
Manufacturer - Gene Name	ABCC1
Gene Full Name	Multidrug resistance-associated protein 1
Background	The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.
Immunogen	Recombinant full-length human ABCC1 protein
Contents	Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Purification	200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.
Concentration	Purified antibody with BSA and azide at 200ug/ml
Manufacturer - Research Category	ATPases, Cancer, Channels, Drug Metabolism, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Plasma Membrane, Signal Transduction
Protein Function	Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Subcellular Localization	Cytoplasmic and Cell Surface
Short Description	Boster Bio Anti-MRP1 / ABCC1 (Multidrug Resistance Related Protein 1) Monoclonal Antibody (Catalog # M00872). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-MRP1 / ABCC1 (Multidrug Resistance Related Protein 1) Monoclonal Antibody (Catalog # M00872). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.
Tissue Specificity	Lung, testis and peripheral blood mononuclear cells.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M00872-datasheet.pdf

BOS-M00872-safety-datasheet.pdf