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Anti-Human IL22 DyLight® 550 conjugated Antibody(monoclonal, 7F2) European Partner

Item no. BOS-M00963-Dyl550
Manufacturer Boster
Amount 100 ug/vial
Category
Type Antibody Primary
Format Liquid
Applications FC
Clone 7F2
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Conjugate/Tag DyLight 550
Sensitivity >5000 cells
Citations 1. Dumoutier, L., Van Roost, E., Ameye, G., Michaux, L., Renauld, J.-C. IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes. Genes Immunity 1: 488-494, 2000.
2. Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A (2001). "Interleukin-10 and the interleukin-10 receptor". Annu. Rev. Immunol. 19: 683–765.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Interleukin-22; IL-22; Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; IL-TIF; IL22; ILTIF, ZCYTO18; UNQ3099/PRO10096
Available
Specificity No cross reactivity with other proteins.
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Mouse IgG1
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Observed Molecular Weight
39 kDa
Clonality
Monoclonal
Application Details
Flow Cytometry (Fixed), 1-3?g/1x106 cells
Manufacturer - Gene Name
IL22
Gene Full Name
interleukin 22
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Interleukin-22 (IL-22), also known as ILTIF, is protein that in humans is encoded by the IL22 gene. IL-22 a member of a group of cytokines called the IL-10 family or IL-10 superfamily, a class of potent mediators of cellular inflammatory responses. Using FISH, the IL22 gene is mapped to chromosome 12q15, close to the IFNG and the herpesvirus saimiri-induced AK155 genes. IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins. It also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. In some contexts, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by the often co-expressed cytokine IL-17A.
Immunogen
E. coli-derived human IL-22 recombinant protein (Position: A34-I179). Human IL-22 shares 81.4% amino acid (aa) sequence identity with mouse IL-22.
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Adapters, Cytokines, Immunology, Innate Immunity, Interleukins, Macrophage/Inflammation, Signal Transduction, Transmembrane
Protein Function
Cytokine that contributes to the inflammatory response in vivo.
Subcellular Localization
Secreted.
Description
Boster Bio Anti-Human IL22 DyLight® 550 conjugated Antibody (monoclonal, 7F2) catalog # M00963-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
Tissue Specificity
Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
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