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Anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Monoclonal Antibody

Anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Monoclonal Antibody

Item no.	BOS-M01120
Manufacturer	Boster
Amount	100 ug
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	IHC
Clone	LHCGR/1417
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Lutropin-choriogonadotropic hormone receptor;LH/CG-R;Luteinizing hormone receptor;LHR;LSH-R;LHCGR;LCGR, LGR2, LHRHR;
Available
Manufacturer - Category	Primary Antibodies, Monoclonal Antibodies, 2279
Storage Conditions	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Observed Molecular Weight	78643 MW
Clonality	Monoclonal
Application Details	Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
Manufacturer - Gene Name	LHCGR
Gene Full Name	Lutropin-choriogonadotropic hormone receptor
Background	Recognizes a protein of 78-85kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
Immunogen	Recombinant fragment (around aa 70-410) of human LHCGR protein (exact sequence is proprietary)
Contents	Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Purification	200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.
Concentration	Purified antibody with BSA and azide at 200ug/ml
Manufacturer - Research Category	Endocrine System, G Protein Signaling, More Gpcr, Neuroscience, Neurotransmission, Receptors / Channels, Signal Transduction, Signaling Pathway
Protein Function	Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Subcellular Localization	Cell Surface and Cytoplasm
Short Description	Boster Bio Anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Monoclonal Antibody (Catalog # M01120). Tested in IHC applications. This antibody reacts with Human.
Description	Boster Bio Anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Monoclonal Antibody (Catalog # M01120). Tested in IHC applications. This antibody reacts with Human.
Tissue Specificity	Gonadal and thyroid cells.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M01120-datasheet.pdf

BOS-M01120-safety-datasheet.pdf