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Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody

Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody

Item no.	BOS-M01127
Manufacturer	Boster
Amount	100 ul
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC
Clone	HBB-19
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	14-3-3 protein sigma;Epithelial cell marker protein 1;Stratifin;SFN;HME1;
Available
Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	80 kDa
Calculated Molecular weight	27774 MW
Clonality	Monoclonal
Application Details	WB 1:1000-1:2000 IHC 1:50-1:200
Manufacturer - Gene Name	SFN
Gene Full Name	14-3-3 protein sigma
Immunogen	A synthesized peptide derived from human 14-3-3 sigma
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Adapters, Cell Type Marker, Cytoplasmic, Neural Signal Transduction, Neurology Process, Neuron Marker, Neuroscience, Signal Transduction, Signaling Pathways, Stem Cells, Synapse Marker
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
Subcellular Localization	Cytoplasm. Nucleus. Secreted. May be secreted by a non-classical secretory pathway.
Description	Boster Bio Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody catalog # M01127. Tested in WB, IHC applications. This antibody reacts with Human, Rat.
Tissue Specificity	Present mainly in tissues enriched in stratified squamous keratinizing epithelium.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M01127-datasheet.pdf

BOS-M01127-safety-datasheet.pdf