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Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody, Clone#RM259

Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody, Clone#RM259

Item no.	BOS-M01577-2
Manufacturer	Boster
Amount	100 ul
Category	Antibodies Cell Biology Cell Movement Cell Adhesion Western Blot Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB
Clone	RM259
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cadherin-2;CDw325;Neural cadherin;N-cadherin;CD325;CDH2;CDHN, NCAD;
Available
Manufacturer - Category	Primary Antibodies, Monoclonal Antibodies, Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	99809 MW
Clonality	Monoclonal
Application Details	WB: 1:1000-1:2000 dilution
Manufacturer - Gene Name	CDH2
Gene Full Name	Cadherin-2
Immunogen	A peptide corresponding to Human N-Cadherin
Contents	50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification	Protein A affinity purified from an animal origin-free culture supernatant
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cadherins, Cell Adhesion, Cytoskeleton/ECM, Signal Transduction
Protein Function	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).
Subcellular Localization	Cell membrane; Single-pass type I membrane protein. Cell membrane, sarcolemma. Cell junction. Cell surface. Colocalizes with TMEM65 at the intercalated disk in cardiomyocytes. Colocalizes with OBSCN at the intercalated disk and at sarcolemma in cardiomyocytes.
Short Description	Boster Bio Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody, Clone#RM259 (Catalog # M01577-2). Tested in WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-N-Cadherin-2 CDH2 CD325-Rabbit Monoclonal Antibody, Clone#RM259 (Catalog # M01577-2). Tested in WB applications. This antibody reacts with Human.
Predicted Reactivity	Mouse, Rat

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M01577-2-datasheet.pdf

BOS-M01577-2-safety-datasheet.pdf