Anti-Parathyroid Hormone Receptor 1 Monoclonal Antibody

Rabbit Monoclonal Antibodies

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

22744 MW

WB 1:500-1:2000
IP 1:50

Claudin-1

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Endocrine System, Growth Factors/Hormones, Neuroscience, Signal Transduction

Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an in effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions (PubMed:23407391).

Boster Bio Anti-Parathyroid Hormone Receptor 1 Monoclonal Antibody catalog # M01588. Tested in WB, IP applications. This antibody reacts with Human.