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Anti-Ezrin Rabbit Monoclonal Antibody

Anti-Ezrin Rabbit Monoclonal Antibody

Item no.	BOS-M01750
Manufacturer	Boster
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Adenocarcinoma Immunohistochemistry Western Blot Primary Antibodies Microglia Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC
Clone	AAAI-5
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Ezrin;Cytovillin;Villin-2;p81;EZR;VIL2;
Available
Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	111 kDa
Calculated Molecular weight	69413 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:50-1:200
Manufacturer - Gene Name	EZR
Gene Full Name	Ezrin
Immunogen	A synthesized peptide derived from human Ezrin
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Actin Binding Proteins, Actin, etc., Adapters, Cancer, Cytoplasmic, Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Protein Phosphorylation, Signal Transduction
Protein Name	Lysosome-associated membrane glycoprotein 2 (Lamp2)
Protein Function	Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Subcellular Localization	Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Localization to the apical membrane of parietal cells depends on the interaction with MPP5. Localizes to cell extensions and peripheral processes of astrocytes (By similarity). Microvillar peripheral membrane protein (cytoplasmic side).
Description	Boster Bio Anti-Ezrin Rabbit Monoclonal Antibody catalog # M01750. Tested in WB, IHC applications. This antibody reacts with Human.
Tissue Specificity	Expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. Weakly expressed in brain stem and diencephalon. Stronger expression was detected in gray matter of frontal lobe compared to white matter (at protein level). Component of the microvilli of intestinal epithelial cells. Preferentially expressed in astrocytes of hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Not detected in neurons in most tissues studied.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M01750-datasheet.pdf

BOS-M01750-safety-datasheet.pdf