Anti-Human AMPK beta 2 DyLight® 488 conjugated PRKAB2 Antibody(monoclonal, 6G1)

Mouse IgG2b

39 kDa

Flow Cytometry (Fixed), 1-3?g/1x10⁶ cells

protein kinase, AMP-activated, beta 2 non-catalytic subunit

5'-AMP-activated protein kinase subunit beta-2 is an enzyme that in humans is encoded by the PRKAB2 gene. The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. It is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Apoptosis, Apoptotic Markers, Cancer, Cancer Metabolism, Cardiovascular, Cell Biology, Cell Death, Cytochromes, Energy Metabolism, Energy Transfer Pathways, Integration Of Energy, Integration Of Energy Metabolism, Invasion/Microenvironment, Lipases, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Oxidative Phosphorylation, Pathways and Processes, Signal Transduction

Boster Bio Anti-Human AMPK beta 2 DyLight® 488 conjugated PRKAB2 Antibody (monoclonal, 6G1) catalog # M05077-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.