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Anti-Mast Cell Tryptase Rabbit Monoclonal Antibody

Anti-Mast Cell Tryptase Rabbit Monoclonal Antibody

Item no.	BOS-M08039
Manufacturer	Boster
Amount	100 ul
Category	Antibodies Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, IHC
Clone	FHH-20
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Tryptase alpha/beta-1;Tryptase-1;3.4.21.59;Tryptase I;Tryptase alpha-1;TPSAB1;TPS1, TPS2, TPSB1;
Available
Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	100 kDa
Calculated Molecular weight	30515 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:50-1:200 IP 1:50
Manufacturer - Gene Name	TPSAB1
Gene Full Name	Tryptase alpha/beta-1
Immunogen	A synthesized peptide derived from human Mast Cell Tryptase
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Amino Acid Metabolism, Amino Acids, Cancer, Immunology, Innate Immunity, Macrophage/Inflammation, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction
Protein Name	T-cell surface glycoprotein CD3 zeta chain
Protein Function	Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315).
Subcellular Localization	Secreted. Released from the secretory granules upon mast cell activation.
Description	Boster Bio Anti-Mast Cell Tryptase Rabbit Monoclonal Antibody catalog # M08039. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin; in these tissues, isoform 1 is predominant. Isoform 2 is expressed in aorta, spleen, and breast tumor, with highest levels in the endothelial cells of some blood vessels surrounding the aorta, as well as those surrounding the tumor and low levels, if any, in mast cells (at protein level).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M08039-datasheet.pdf

BOS-M08039-safety-datasheet.pdf