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Anti-Phospho-Histone H2A/H4 (Ser1) H2AFX Rabbit Monoclonal Antibody, Clone#RM216

Anti-Phospho-Histone H2A/H4 (Ser1) H2AFX Rabbit Monoclonal Antibody, Clone#RM216

Item no.	BOS-P00241
Manufacturer	Boster
Amount	100 ug
Category	Neuroscience Neural Epigenetics Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ICC, ELISA
Clone	RM216
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Histone H2AX;H2a/x;Histone H2A.X;H2AFX;H2AX;
Available
Specificity	Human,Vertebrates
Manufacturer - Category	Monoclonal Antibodies, Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	15145 MW
Clonality	Monoclonal
Application Details	WB: 0.5 ug/mL - 2 ug/mL ICC: 1 ?g/mL - 2 ?g/mL ELISA: 0.2 ug/mL - 1 ug/mL Luminex: 0.1 ug/mL – 1 ug/mL.
Manufacturer - Gene Name	H2AFX
Gene Full Name	Histone H2AX
Immunogen	An unmodified peptide corresponding to the N-terminus of Histone H3.
Contents	50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification	Protein A affinity purified from an animal origin-free culture supernatant
Concentration	1 mg/mL
Manufacturer - Research Category	2339, DNA/RNA, DNA Damage Response, Epigenetics and Nuclear Signaling, Histones
Protein Function	Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation.
Subcellular Localization	Nucleus. Chromosome.
Short Description	Boster Bio Anti-Phospho-Histone H2A/H4 (Ser1) H2AFX Rabbit Monoclonal Antibody, Clone#RM216 (Catalog # P00241). Tested in WB, ICC, ELISA, Luminex applications. This antibody reacts with Human, Vertebrates.
Description	Boster Bio Anti-Phospho-Histone H2A/H4 (Ser1) H2AFX Rabbit Monoclonal Antibody, Clone#RM216 (Catalog # P00241). Tested in WB, ICC, ELISA, Luminex applications. This antibody reacts with Human, Vertebrates.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-P00241-datasheet.pdf

BOS-P00241-safety-datasheet.pdf