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Anti-Phospho-Shb (Tyr246) Antibody

Anti-Phospho-Shb (Tyr246) Antibody

Item no.	BOS-P02109
Manufacturer	Boster
Amount	100 ul
Category	Neuroscience Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	SH2 domain-containing adapter protein B;SHB;
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	55042 MW
Clonality	Polyclonal
Application Details	Western blotting: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications.
Manufacturer - Gene Name	SHB
Gene Full Name	SH2 domain-containing adapter protein B
Immunogen	Synthesized peptide derived from human Shb around the phosphorylation site of Y246.
Contents	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	Adapters, Cytoplasmic, Developmental Biology, Embryogenesis, Embryonic Stem Cells, Intracellular, Signal Transduction, Stem Cells, Surface Molecules
Protein Function	Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic- FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Subcellular Localization	Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Associates with membrane lipid rafts upon TCR stimulation.
Short Description	Boster Bio Anti-Phospho-Shb (Tyr246) Antibody (Catalog # P02109). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-Phospho-Shb (Tyr246) Antibody (Catalog # P02109). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Widely expressed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-P02109-datasheet.pdf

BOS-P02109-safety-datasheet.pdf