Manufacturer |
Boster
|
Category |
|
Type |
Elisa-Kit |
Specific against |
Human |
Applications |
ELISA |
Amount |
96 wells/kit, with removable strips. |
Item no. |
BOS-EK0397 |
Targets |
IL2 |
eClass 6.1 |
32160605 |
eClass 9.0 |
32160605 |
Available |
|
Manufacturers Product Category |
PicoKine® ELISA Kits |
Manufacturers Research Category |
Adaptive Immunity, Cell Type Markers, Cytokines, Immunology, Innate Immunity, Interleukins, T Cells |
Short Description |
Human IL-2/Interleukin-2 ELISA Kit PicoKine® (96 Tests). Quantitate Human IL2 in cell culture supernatants, serum and plasma ( heparin, EDTA, citrate). Sensitivity: 1pg/ml. |
Description |
Human IL-2/Interleukin-2 ELISA Kit PicoKine® (96 Tests). Quantitate Human IL2 in cell culture supernatants, serum and plasma ( heparin, EDTA, citrate). Sensitivity: 1pg/ml. |
Background |
Interleukin-2 (IL2), formerly referred to as T-cell growth factor, is a powerfully immunoregulatory lymphokine that is produced by lectin- or antigen-activated T cells. It is produced not only by mature T lymphocytes on stimulation but also constitutively by certain T-cell lymphoma cell lines. The lymphokine interleukin-2 (IL-2) is responsible for autocrine cell cycle progression and regulation of immune responses. IL-2 expression in mature thymocytes and T cells has been found to be tightly controlled by monoallelic expression. IL-2 can act as a growth hormone for both B and T lymphocytes. The human gene for interleukin 2 (IL2) is assigned to chromosome 4. Human IL-2 is a 15.5KDa glycoprotein, consisting of 153 amino acids in precursor form and 133 amino acids in mature form. |
Gene Name |
IL2 |
Application Details |
Dilution ratio of 1:1, concentration in serum and plasma is less than the lowest standard, 15.6 pg/ml. |
Immunogen |
Expression system for standard: E.coli; Immunogen sequence: A21-T153 |
Cross-reactivity |
There is no detectable cross-reactivity with other relevant proteins. |
Sample Type |
cell culture supernatants, serum and plasma ( heparin, EDTA, citrate). |
Capture antibody|Detection antibody |
monoclonal antibody from mouse|polyclonal antibody from goat |
Storage |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
Anticoagulant |
heparin, EDTA or citrate |
Gene Full Name |
Interleukin-2 |
Molecular Weight |
17628 MW |
Protein Function |
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells. |
Subcellular Localization |
Secreted. |
Protein Name |
Interleukin-2 |
Sequence Similarities |
Belongs to the IL-2 family. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
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