Comparison

Human CD320 / 8D6A / TCblR ELISA Kit PicoKine®

Manufacturer Boster
Category
Type Elisa-Kit
Specific against Human
Applications ELISA
Amount 96 wells/kit, with removable strips.
Item no. BOS-EK1255
Targets CD320, CD209
eClass 6.1 32160605
eClass 9.0 32160605
Available
Manufacturers Product Category
PicoKine® ELISA Kits
Manufacturers Research Category
Adaptive Immunity, B Cells, Cell Biology, Cell Cycle, Cell Differentiation, Developmental Biology, Immunology, Organogenesis
Short Description
Human CD320 / 8D6A / TCblR ELISA Kit PicoKine® (96 Tests). Quantitate Human CD320 in cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 10pg/ml.
Description
Human CD320 / 8D6A / TCblR ELISA Kit PicoKine® (96 Tests). Quantitate Human CD320 in cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 10pg/ml.
Background
CD320 (cluster of differentiation 320), also known as 8D6A or TCBLR, is a human gene. It is mapped to chromosome 19p13.2. This gene encodes the transcobalamin receptor that is expressed at the cell surface. It mediates the cellular uptake of transcobalamin bound cobalamin (vitamin B12), and the expression of CD320 enhanced B-cell proliferation and immunoglobulin secretion. Mutations in this gene are associated with methylmalonic aciduria. It has been found that antagonists of the CD320 signaling pathway may counter the growth of follicular lymphomas or other tumors that metastasize to lymphoid follicles. CD320 is also a specific receptor for uptake of TCN2-bound cobalamin.
Gene Name
CD320
Application Details
Dilution ratio of 1:1, concentration in serum and plasma is 100-360 pg/ml.
Immunogen
Expression system for standard: NS0; Immunogen sequence: S36-Y229
Cross-reactivity
There is no detectable cross-reactivity with other relevant proteins.
Sample Type
cell culture supernatants, serum, plasma (heparin, EDTA) and urine.
Capture antibody|Detection antibody
monoclonal antibody from mouse|polyclonal antibody from goat
Storage
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Anticoagulant
heparin or EDTA
Gene Full Name
CD320 antigen
Molecular Weight
28991 MW
Protein Function
Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin..
Subcellular Localization
Membrane ; Single-pass type I membrane protein.
Tissue Specificity
Expressed abundantly on follicular dendritic cells (FDCs)..
Protein Name
CD320 antigen

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 96 wells/kit, with removable strips.
Available: In stock
available

Delivery expected until 5/2/2024 

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