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Caspase 1 Colorimetric Cell-Based ELISA Kit

Caspase 1 Colorimetric Cell-Based ELISA Kit

Item no.	BOS-EKC1083
Manufacturer	Boster
Amount	1 kit, containing one 96-well plate and all necessary reagents
Category	Neuroscience Neural Signaling Cell Biology Cell Status Apoptosis ELISA ELISA & Immunoassays ELISA Kits Immunoassay
Type	Elisa-Kit
Applications	ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	CASP-1;caspase-1;ICE;IL-1 beta converting enzyme;IL-1BC;IL1BCE;interleukin-1 beta convertase;interleukin-1 beta converting enzyme;p45
Available
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Observed Molecular Weight	45159 MW
Manufacturer - Gene Name	CASP1
Gene Full Name	Caspase-1
Sample Type	Cell lines
Protein Function	Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of MB21D1/cGAS, rendering it inactive (PubMed:28314590).
Subcellular Localization	Cytoplasm.
Short Description	The Caspase 1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Caspase 1 protein expression profile in cells. The kit can be used for measuring the relative amounts of Caspase 1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Caspase 1.
Description	The Caspase 1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Caspase 1 protein expression profile in cells. The kit can be used for measuring the relative amounts of Caspase 1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Caspase 1.
Tissue Specificity	Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-EKC1083-datasheet.pdf

BOS-EKC1083-safety-datasheet.pdf