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CREB-BP Colorimetric Cell-Based ELISA Kit

CREB-BP Colorimetric Cell-Based ELISA Kit

Item no.	BOS-EKC1141
Manufacturer	Boster
Amount	1 kit, containing one 96-well plate and all necessary reagents
Category	Neuroscience Molecular Targets for Neuroscience Neural Signaling ELISA ELISA & Immunoassays ELISA Kits Immunoassay
Type	Elisa-Kit
Applications	ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	CREB-binding protein;CREBBP;CBP
Available
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Observed Molecular Weight	265351 MW
Manufacturer - Gene Name	CREBBP
Gene Full Name	CREB-binding protein
Sample Type	Cell lines
Protein Function	Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK- ARNTL/BMAL1 heterodimers. Acetylates PCNA; acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902).
Subcellular Localization	Cytoplasm. Nucleus. Recruited to nuclear bodies by SS18L1/CREST. In the presence of ALX1 relocalizes from the cytoplasm to the nucleus.
Short Description	The CREB-BP Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CREB-BP protein expression profile in cells. The kit can be used for measuring the relative amounts of CREB-BP in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CREB-BP.
Description	The CREB-BP Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CREB-BP protein expression profile in cells. The kit can be used for measuring the relative amounts of CREB-BP in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CREB-BP.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-EKC1141-datasheet.pdf

BOS-EKC1141-safety-datasheet.pdf