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IkappaB-alpha Colorimetric Cell-Based ELISA Kit

IkappaB-alpha Colorimetric Cell-Based ELISA Kit

Item no.	BOS-EKC1311
Manufacturer	Boster
Amount	1 kit, containing one 96-well plate and all necessary reagents
Category	Metabolism Cholesterol & Lipid Metabolism ELISA ELISA & Immunoassays ELISA Kits Immunoassay Immunostaining
Type	Elisa-Kit
Applications	ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	I-kappa-B-alpha,IkappaBalpha,IKBA,MAD3,Major histocompatibility complex enhancer-binding protein MAD3,NF-kappaB inhibitor alpha,NFKBI,NFKBIA,RL/IF-1
Available
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Molecular Weight	35609 MW
Gene Name	NFKBIA
Gene Full Name	NF-kappa-B inhibitor alpha
Protein Function	Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Subcellular Localization	Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export.
Description	The IkappaB-alpha Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor IkappaB-alpha protein expression profile in cells. The kit can be used for measuring the relative amounts of IkappaB-alpha in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on IkappaB-alpha.
Sample Type	Cell lines

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-EKC1311-datasheet.pdf

BOS-EKC1311-safety-datasheet.pdf