Comparison

Patched Colorimetric Cell-Based ELISA Kit European Partner

Item no. BOS-EKC1441
Manufacturer Boster
Amount 1 kit, containing one 96-well plate and all necessary reagents
Category
Type Elisa-Kit
Applications ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Sensitivity >5000 cells
ECLASS 10.1 32160605
ECLASS 11.0 32160605
UNSPSC 41116126
Alias Protein patched homolog 1,PTC,PTC1,PTCH1,PTCH
Available
Manufacturer - Category
Cell-Based ELISA Kits
Storage Conditions
Store at 4°C for up to 6 months.
Molecular Weight
160545 MW
Gene Name
PTCH1
Gene Full Name
Protein patched homolog 1
Protein Function
Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Subcellular Localization
Cell membrane; Multi-pass membrane protein.
Description
The Patched Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Patched protein expression profile in cells. The kit can be used for measuring the relative amounts of Patched in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Patched.
Tissue Specificity
In the adult, expressed in brain, lung, liver, heart, placenta, skeletal muscle, pancreas and kidney. Expressed in tumor cells but not in normal skin.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 kit, containing one 96-well plate and all necessary reagents
Available: In stock
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