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WAVE1 Colorimetric Cell-Based ELISA Kit

WAVE1 Colorimetric Cell-Based ELISA Kit

Item no.	BOS-EKC1598
Manufacturer	Boster
Amount	1 kit, containing one 96-well plate and all necessary reagents
Category	Oncology Neuroscience Neural Signaling By Cell Type ELISA ELISA & Immunoassays ELISA Kits Immunoassay
Type	Elisa-Kit
Applications	ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Wiskott-Aldrich syndrome protein family member 1;WASP family protein member 1;Protein WAVE-1;Verprolin homology domain-containing protein 1;WASF1;KIAA0269, SCAR1, WAVE1;
Available
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Observed Molecular Weight	61652 MW
Manufacturer - Gene Name	WASF1
Gene Full Name	Wiskott-Aldrich syndrome protein family member 1
Protein Function	Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). As component of the WAVE1 complex, required for BDNF- NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).
Subcellular Localization	Cytoplasm, cytoskeleton. Cell junction, synapse. Cell junction, focal adhesion. Dot-like pattern in the cytoplasm. Concentrated in Rac-regulated membrane-ruffling areas (PubMed:9889097). Partial translocation to focal adhesion sites might be mediated by interaction with SORBS2 (PubMed:18559503). In neurons, colocalizes with activated NTRK2 after BDNF addition in endocytic sites through the association with TMEM108 (By similarity).
Short Description	The WAVE1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor WAVE1 protein expression profile in cells. The kit can be used for measuring the relative amounts of WAVE1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on WAVE1.
Description	The WAVE1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor WAVE1 protein expression profile in cells. The kit can be used for measuring the relative amounts of WAVE1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on WAVE1.
Tissue Specificity	Highly expressed in brain. Lowly expressed in testis, ovary, colon, kidney, pancreas, thymus, small intestine and peripheral blood.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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BOS-EKC1598-datasheet.pdf

BOS-EKC1598-safety-datasheet.pdf