BCL-2 (Phospho-Thr56) Colorimetric Cell-Based ELISA Kit

Store at 4°C for up to 6 months.

BCL2

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).

The BCL-2 (Phospho-Thr56) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor BCL-2 (Phospho-Thr56) protein expression profile in cells. The kit can be used for measuring the relative amounts of BCL-2 (Phospho-Thr56) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on BCL-2 (Phospho-Thr56).

Expressed in a variety of tissues.