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Ezrin (Phospho-Tyr353) Colorimetric Cell-Based ELISA Kit

Ezrin (Phospho-Tyr353) Colorimetric Cell-Based ELISA Kit

Item no.	BOS-EKC2405
Manufacturer	Boster
Amount	1 kit, containing two 96-well plates and all necessary reagents
Category	Oncology Neuroscience Neural Lineage Markers By Cell Type Carcinoma Adenocarcinoma ELISA ELISA & Immunoassays ELISA Kits Immunoassay Microglia Markers
Type	Elisa-Kit
Applications	ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Ezrin;Cytovillin;Villin-2;p81;EZR;VIL2;
Available
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Observed Molecular Weight	69413 MW
Manufacturer - Gene Name	EZR
Gene Full Name	Ezrin
Protein Function	Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Subcellular Localization	Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell projection, microvillus. Localization to the apical membrane of parietal cells depends on the interaction with MPP5. Localizes to cell extensions and peripheral processes of astrocytes (By similarity). Microvillar peripheral membrane protein (cytoplasmic side).
Short Description	The Ezrin (Phospho-Tyr353) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Ezrin (Phospho-Tyr353) protein expression profile in cells. The kit can be used for measuring the relative amounts of Ezrin (Phospho-Tyr353) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Ezrin (Phospho-Tyr353).
Description	The Ezrin (Phospho-Tyr353) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Ezrin (Phospho-Tyr353) protein expression profile in cells. The kit can be used for measuring the relative amounts of Ezrin (Phospho-Tyr353) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Ezrin (Phospho-Tyr353).
Tissue Specificity	Expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. Weakly expressed in brain stem and diencephalon. Stronger expression was detected in gray matter of frontal lobe compared to white matter (at protein level). Component of the microvilli of intestinal epithelial cells. Preferentially expressed in astrocytes of hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Not detected in neurons in most tissues studied.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-EKC2405-datasheet.pdf

BOS-EKC2405-safety-datasheet.pdf