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FOXO4 (Phospho-Ser197) Colorimetric Cell-Based ELISA Kit

FOXO4 (Phospho-Ser197) Colorimetric Cell-Based ELISA Kit

Item no.	BOS-EKC2413
Manufacturer	Boster
Amount	1 kit, containing two 96-well plates and all necessary reagents
Category	Oncology ELISA ELISA & Immunoassays ELISA Kits Immunoassay By Organ Skin Cancer Immunostaining
Type	Elisa-Kit
Applications	ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Forkhead box protein O4,Fork head domain transcription factor AFX1,FOXO4,AFX,AFX1,MLLT7
Available
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Molecular Weight	53684 MW
Gene Name	FOXO4
Gene Full Name	Forkhead box protein O4
Protein Function	Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Subcellular Localization	Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm.
Description	The FOXO4 (Phospho-Ser197) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor FOXO4 (Phospho-Ser197) protein expression profile in cells. The kit can be used for measuring the relative amounts of FOXO4 (Phospho-Ser197) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on FOXO4 (Phospho-Ser197).
Tissue Specificity	Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform zeta is most abundant in the liver, kidney, and pancreas.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-EKC2413-datasheet.pdf

BOS-EKC2413-safety-datasheet.pdf