SOX2 SRY (sex determining region Y)-box 2 Human Recombinant Protein

Solution

The SOX2 solution contains 20mM Tris-HCl pH -8, 2mM DTT, 0.2M NaCl & 40% glycerol.

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).