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Human IL-1 beta Recombinant Protein

Human IL-1 beta Recombinant Protein

Item no.	BOS-R00101-6
Manufacturer	Boster
Amount	5 ug
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Neural Signaling Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines
Type	Proteins
Format	Lyophilized
Applications	Cell Culture
Specific against	other
Dry ice	Yes
Sequence	APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS (153)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Interleukin-1 beta; IL-1 beta; Catabolin; IL1B; IL1F2
Available
Manufacturer - Category	Recombinant Proteins
Storage Conditions	Store at -20Â°C for one year. Avoid repeated freeze-thaw cycles.
Manufacturer - Gene Name	IL1B
Contents	Lyophilized without carrier protein.
Purification	Ion-exchange chromatography.
Manufacturer - Research Category	Atherosclerosis, Cardiovascular, Cytokines, Immunology, Innate Immunity, Interleukins, Metabolism, Obesity, Vascular Inflammation
Protein Function	Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.
Subcellular Localization	Cytoplasm, cytosol.
Short Description	IL-1 beta (IL-1?) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Human IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.
Description	IL-1 beta (IL-1?) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Human IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.
Tissue Specificity	Expressed in activated monocytes/macrophages (at protein level).
Bioactivity/Biological Activity	In testing.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-R00101-6-datasheet.pdf

BOS-R00101-6-safety-datasheet.pdf