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Diallyl disulfide

Diallyl disulfide

Item no.	HY-W015635-50mg
Manufacturer	MedChem Express
CASRN	2179-57-9
Amount	50 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 50 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.33
Citations	[1]Gupta N, et al. Garlic and garlic-derived compounds inhibit human squalene monooxygenase. J Nutr. 2001;131(6):1662-1667. \|[2]You-Sheng Huang, et al. Diallyl disulfide inhibits the proliferation of HT-29 human colon cancer cells by inducing differentially expressed genes. Mol Med Rep. 2011 May-Jun;4(3):553-9.\|[3]Xiaoyou Wei, et al. Acute Diallyl Disulfide Administration Prevents and Reveres Lipopolysaccharide-Induced Depression-Like Behaviors in Mice via Regulating Neuroinflammation and Oxido-Nitrosative Stress. Inflammation. 2021 Aug;44(4):1381-1395.\|[4]Aline de Oliveira Pontes Cardoso, et al. Diallyl disulfide prevents cigarette smoke-induced emphysema in mice. Pulm Pharmacol Ther. 2021 Aug:69:102053.
Smiles	C=CCSSCC=C
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Others
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, stored under nitrogen)
Molecular Weight	146.27
Product Description	Diallyl disulfide, an active compound in garlic oil, is an orally active human squalene monooxygenase inhibitor with an IC50 of 400 μM for squalene epoxidation. Diallyl disulfide exhibits obvious anti-inflammatory, anti-oxidative, antidepressant and anti-tumor activities[1][2][3][4].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Others
Clinical information	No Development Reported

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HY-W015635-50mg-safety-datasheet.pdf