« Back
Home /
Tubulin polymerization-IN-28

Tubulin polymerization-IN-28

Item no.	HY-149021-1ea
Manufacturer	MedChem Express
CASRN	2481404-89-9
Amount	1 ea
Quantity options	100 mg 1 ea
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Citations	[1]Chong Zhang,et al. NQO1-selective activated prodrugs of combretastatin A-4: Synthesis and biological evaluation. Bioorg Chem. 2020 Oct;103:104200.
Smiles	COC1=CC(/C=C\C2=CC(OC)=C(C=C2)OC(N(CCN(C(CC(C)(C3=C(C(C(C)=C(C3=O)C)=O)C)C)=O)C)C)=O)=CC(OC)=C1OC
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; Microtubule/Tubulin
Shipping Temperature	Room temperature
Molecular Weight	662.77
Product Description	Tubulin polymerization-IN-28 (compound-4) is a microtubule protein polymerization inhibitor with highly selective anticancer activity. Tubulin polymerization-IN-28 can be activated by NQO1 and effectively release combretastatin A-4 to kill tumor cells. Tubulin polymerization-IN-28 can induce cell apoptosis and be used in anti-cancer research[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Clinical information	Phase 1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 ea

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question