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Recombinant Human Plasminogen activator inhibitor 1 (SERPINE1), partial

Recombinant Human Plasminogen activator inhibitor 1 (SERPINE1), partial

Item no.	BM-RPC25868-100ug
Manufacturer	Biomatik
Amount	100ug
Category	Oncology Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Senescence By Organ Breast Cancer
Type	Proteins Recombinant
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Endothelial plasminogen activator inhibitorSerpin E1
Similar products	Endothelial plasminogen activator inhibitorSerpin E1
Available
Gene Name	SERPINE1
Alternative Names	Endothelial plasminogen activator inhibitorSerpin E1
Uniprot	P05121
Source	E.coli
Expression Region	24-401aa
AA Sequence	VHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFS PYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKG MAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKL VQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWV KTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQW KTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNY TEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEV PLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSL ETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPL HVAQALQKVKIEVNESGTVASSSTAVIVSARMAPE EIIMDRPFLFVVRHNPTGTVLFMGQVME
Sequence Info	Partial
Tag Info	N-terminal 6xHis-tagged
Theoretical MW	46.7 kDa
Purity	>90% as determined by SDS-PAGE.
Storage Buffer	Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level	Not tested
Biological Activity	Not tested
Shipping Condition	Ice packs
Storage	Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date	1 year
Restriction	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance	Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.
Function	Serine protease inhibitor. Inhibits TMPRSS7
Involvement in disease	Plasminogen activator inhibitor-1 deficiency (PAI-1D)
Subcellular location	Secreted
Protein Families	Serpin family
Tissue Specificity	Expressed in endothelial cells (PubMed:2430793, PubMed:3097076). Found in plasma, platelets, and hepatoma and fibrosarcoma cells.
Paythway	HIF-1signalingpathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 9/4/2025

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